The Synthesis of Low-Fluorinated Compounds Based on Polyfluoroaromatic Compounds

 

G. G. Furin

Siberian Branch of Russian Academy of Sciences Novosibirsk N.N. Vorozhtsov Institute of Organic Chemistry of SB RAS

 

  Abstract

The analysis of obtaining methods for low-fluorinated derivatives of aromatic row including processes of transformation of polyfluoroaromatic compounds had been carried out: using reducing hydrogenolysis of C-F, C-Cl bonds , electrochemical transformation and protodehalogenation by the influence of zinc, copper, nickel in different media. Here the examples on using that processes with the yield of significant semi-products and materials are given.

Table of Contents

1. Introduction

2. Approaches to Synthesis of Partly Fluorinated Benzene Derivatives
2.1. Reductive Dehalogenation of Polyfluorochloroarenes by Lithium Aluminium Hydride
2.2. Catalytic Hydration of Polyfluoroaromatic Compounds
2.3. Reductive Dehalogenation of Polyfluoroarenes by P(NEt2)3 in Aqueous Media
2.4. Electrochemical Reduction of Fluorine Containing Benzene Derivatives

3. Protodehalogenation of Polyfluorinated Benzene Derivatives Using Metals
3.1. Copper Influence.
3.2. Zinc Influence in Different Media
3.2.1. Zinc Influence in the Medium of Acids and Bases
3.2.2. Zinc Influence in the Medium of Aqueous Ammonia
3.2.3. Hydrogenolysis of C-F Bond in Polyfluoroaromatic Row Under the Influences of Zinc-Copper Pair in Aqueous Dimethylformamide
3.2.4. Protodehalogenation of Polyfluoroarenes Using Zinc Over a Nickel Salts and Transition Metals Complexes

References